Case Reports
25 August 2025
Vol. 3 No. 1 (2025)

Bilateral continuous thoracic paravertebral block for chronic pancreatitis pain management

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Thoracic paravertebral (TPV) block is a technique that has been shown to be effective for both the prevention and treatment of chronic pain. We report the case of a 42-year-old man with persistent chronic postoperative pain due to a pancreatic pseudocyst. Chronic pancreatitis is characterized by altered pancreatic innervation and neuronal remodeling. This phenomenon leads to chronic and neuropathic pain, which persists for years even in the absence of nociceptive stimuli. Laparoscopic surgical drainage is the method of choice for the treatment of pseudocysts of the pancreas. Despite laparoscopic gastropancreatic surgery for the removal of the pseudocyst, the patient continued to report persistent pain. We describe our experience with a continuous TPV block, which resulted in complete pain resolution.

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1. Faber CL, Deem JB, Campos CA, et al. CNS control of the endocrine pancreas. Diabetologia 2020;63:2086-94. DOI: https://doi.org/10.1007/s00125-020-05204-6
2. Zeggeren LV, Nabbi RB, Kallewaard JW, et al. Pain in chronic pancreatitis. Pain Pract 2025; 25:e70030. DOI: https://doi.org/10.1111/papr.70030
3. Lkhagvasuren B, Mee-Inta O, Zhao ZW, et al. Pancreas-Brain Crosstalk. Front Neuroanat 2021;15:691777. DOI: https://doi.org/10.3389/fnana.2021.691777
4. Wang Y, Omar YA, Agrawal R, Gong Z. Comparison of treatment modalities in pancreatic pseudocyst: A population-based study. World J Gastrointest Surg 2019;11:365-72. DOI: https://doi.org/10.4240/wjgs.v11.i9.365
5. Voscopoulos C, Lema M. When does Acute pain become chronic? Br J Anaesth 2010;105:69-85. DOI: https://doi.org/10.1093/bja/aeq323
6. Demir IE, Friess H, Ceyhan GO. Neural plasticity in pancreatitis and pancreatic cancer. Nat Rev Gastroenterol Hepatol 2015;12:649-59. DOI: https://doi.org/10.1038/nrgastro.2015.166
7. Kim YH, Kim SY, Lee YJ, Kim ED. A Prospective, Randomized Cross-Over Trial of T2 Paravertebral Block as a Sympathetic Block in Complex Regional Pain Syndrome. Pain Physician 2019;22:E417-24. DOI: https://doi.org/10.36076/ppj/2019.22.E417
8. Richardson J, Lönnqvist PA, Naja Z. Bilateral thoracic paravertebral block: potential and practice. Br J Anaesth 2011;106:164-71. DOI: https://doi.org/10.1093/bja/aeq378
9. Goulden MR. The pain of chronic pancreatitis a persistent clinical challenge. Br J Pain 2013;7:8-22. DOI: https://doi.org/10.1177/2049463713479230
10. Demir IE, Tieftrunk E, Maak M, et al. Pain mechanisms in chronic pancreatitis: of a master and his fire. Langenbecks Arch Surg 2011;396:151-60. DOI: https://doi.org/10.1007/s00423-010-0731-1
11. Kirvelä O, Antila H. Thoracic paravertebral block in chronic postoperative pain. Reg Anesth 1992;17:348-50.
12. Hutchins JL, Grandelis AJ, Kaizer AM, Jensen EH. Thoracic paraveretebral block versus thoracic epidural analgesia for post-operative pain control in open pancreatic surgery: A randomized controlled trial. J Clin Anesth 2018;48:41-45. DOI: https://doi.org/10.1016/j.jclinane.2018.04.013
13. Han Y, Dai Y, Shi Y, et al. Ultrasound-guided paravertebral blockade reduced perioperative opioid requirements in pancreatic resection: A randomized controlled trial. Front Surg 2022;9:903441. DOI: https://doi.org/10.3389/fsurg.2022.903441
14. Vayne-Bossert P, Afsharimani B, Good P, et al. Interventional options for the management of refractory cancer pain—what is the evidence? Support Care Cancer 2015;24:1429-38. DOI: https://doi.org/10.1007/s00520-015-3047-4
15. Kulesza G, Tuyakov B, Braczkowska M, et al. Paravertebral blockade – Underrated method of regional anesthesia. Pol Ann Med 2014;21:63-8. DOI: https://doi.org/10.1016/j.poamed.2014.03.002
16. Cammarano CA, Sandhu NPS, Villaluz JE. Localizing the pain: Continuous paravertebral nerve blockade in a patient with Acute pancreatitis. Am J Case Rep 2021;22:e934189-4. DOI: https://doi.org/10.12659/AJCR.934189
17. Brennan L, Fitzgerald J, McCrory C. The use of pulsed radiofrequency treatment for chronic benign pancreatitis pain. Pain Pract 2009;9:135-40. DOI: https://doi.org/10.1111/j.1533-2500.2008.00254.x

How to Cite



Bilateral continuous thoracic paravertebral block for chronic pancreatitis pain management. (2025). Advances in Anesthesia and Pain Medicine, 3(1). https://doi.org/10.4081/aapm.52

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